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BIOC 099 | Principles and Methods in Electrophysiology

September 11, 2019 to September 13, 2019

Registration occurs on a first-come, first-served basis. The deadline for registration is one week before the first day of the course.  If you are unable to register before the deadline, please email: or call 301-496-7977 for space availability. 

NIH Only: Payment approval and authorization is done through your AO or lab manager. Receiving lab approval does not constitute enrollment. Fellows or those being sponsored by their lab can enroll using this form while waiting for authorization of payment

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Contract: SF-182

Course Description:
This 3-day lecture/ hands-on laboratory workshop will cover various applications of electrophysiology in basic science and application driven research. Selected lecture topics will provide a broad background of electrophysiology, from equipment to analysis techniques; technical protocols for electrophysiology procedures and troubleshooting during surgery, data acquisition, experimental integration and online/offline analysis. During this intensive workshop, participants will get the opportunity to discuss basics of electrophysiology and advanced troubleshooting techniques with subject matter experts from both academia and industry.

Lecture and Hands-on Laboratory Topics:
Electrophysiology as a field; Signals of interest including electro-encephalograph (EEG), local field potentials (LFP) multiunit and single unit action potentials (spikes); Electrode Types including Acute electrodes, Chronic electrodes, Surface Electrodes, and Depth Electrodes; Surgical methods; Recording system architecture: Buffers, Differential mode amplification, Analog Digital conversion, Clock signals, Online processing, Data storage, Offline analysis. Recording software basics: Visualization of neural signal, Acquisition channel configurations, Sampling frequency, Filtering, Saving files; Recording software advanced: Advanced visualization, Controlling auxiliary I/O for experimental integration; Wireless recording technologies; Behavioral system integration; File structures; Data analysis in GUI;  Data analysis in MATLAB; Manual and automatic online spike sorting; Noise troubleshooting: Signal acquisition theory, Common sources of noise, Reference and ground schemes, Best practices for low noise recording, Hardware solutions, Software solutions; Closed loop electrophysiology: Closed loop theory and application, MATLAB, C++, Real time processing. Neural Stimulation: Effects and uses of stimulation, Electrodes for stimulation, Waveform parameters, Stimulation hardware. Human Electrophysiology: Application of invasive electrophysiology in human, Regulatory requirements for experiments with humans, Tools for human electrophysiology. 


Who should attend: 

Researchers, clinicians, and academics interested in learning the tools and techniques to acquire and analyze neural signals. Researchers and clinicians interested in the barriers and opportunities in invasive human electrophysiology. Program administrators who are interested in getting a firsthand experience on the concepts and methods used for electrophysiology.

Class size is limited to 24

Workshops generally run from 8:00am - 5:00pm.

Suggested Accommodation:
A special rate is available to all BioTech Workshop attendees. This includes complimentary continental breakfast, guest room Wi-Fi and discounted $15 parking per night. Hotel is within walking distance of the training facility. Reservations can be made online, see below. 
DoubleTree by Hilton Bethesda - Washington DC

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