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BIOC 099 | Principles and Methods in Electrophysiology

December 1, 2020 to December 2, 2020



Registration occurs on a first-come, first-served basis. The deadline for registration is one week before the first day of the course. If you are unable to register before the deadline, please email: or call 301-496-7977 for space availability. 

NIH Fellows or NIH community members being sponsored by their lab and awaiting payment authorization can tentatively hold a seat using the “Reserve A Seat” option.FAES must receive payment within 7 business days after reserving a seat or 3 business days before the start of the workshop, which ever comes first. If payment is not received in this time frame, your reservation will be canceled.

Course Description
This 2-day lecture/ remote laboratory workshop will cover various applications of electrophysiology in basic science and application driven research. Selected lecture topics will provide a broad background of electrophysiology, from equipment to analysis techniques; data acquisition, experimental integration and online/offline analysis. Particular focus will be given towards in vivo extracellular electrophysiology equipment and techniques. During this intensive workshop, participants will get the opportunity to discuss basics of electrophysiology and advanced troubleshooting techniques with subject matter experts from both academia and industry.

Lecture and Remote Laboratory Topics
Electrophysiology as a field; Signals of interest including electro-encephalograph (EEG), local field potentials (LFP) multiunit and single unit action potentials (spikes); Electrode Types including Acute electrodes, Chronic electrodes, Surface Electrodes, and Depth Electrodes; Recording system architecture: Buffers, Differential mode amplification, Analog Digital conversion, Clock signals, Online processing, Data storage, Offline analysis. Recording software basics: Visualization of neural signal, Acquisition channel configurations, Sampling frequency, Filtering, Saving files; Recording software advanced: Advanced visualization, Controlling auxiliary I/O for experimental integration; File structures; Data analysis in GUI;  Data analysis in MATLAB; Manual and automatic online spike sorting; Noise troubleshooting: Signal acquisition theory, Common sources of noise, Reference and ground schemes, Best practices for low noise recording, Hardware solutions, Software solutions; Closed loop electrophysiology: Closed loop theory and application, MATLAB, C++, Real time processing. Neural Stimulation: Effects and uses of stimulation, Electrodes for stimulation, Waveform parameters, Stimulation hardware. Human Electrophysiology: Application of invasive electrophysiology in human, Regulatory requirements for experiments with humans, Tools for human electrophysiology. 


Who should attend
Researchers, clinicians, and academics interested in an overview of the tools and techniques to acquire and analyze extracellular neural signals. Researchers and clinicians interested in the barriers and opportunities in invasive human electrophysiology. Program administrators who are interested in getting a general overview on the concepts and methods used for electrophysiology.

Class size is limited to 18.

Workshops generally run from 8:00am - 5:00pm.

Training Rates
$999.00 - General Rate
Discounted Training Rates
$495.00 - NIH Students (Fellows, Postdocs, Postbacs, Graduate students working at any NIH campus)
$695.00 - NIH Community (Working, Appointed, or Assigned to NIH Campus)
$799.00 - Academia, US Government, US Military

Refund Policy
100% tuition refund for registrations cancelled 14 or more days prior to the start of the workshop.
50% tuition refund for registrations cancelled between 4 to 13 days prior to the start of the workshop.
No refund will be issued for registrations cancelled 3 days or less prior to the start of the workshop.

All cancellations must be received in writing via email to Ms. Carline Coote at
Cancellations received after hours are time marked for the following day. 
All refund payments will be processed by the start of the initial workshop.

Course Cancellation Policy
FAES reserves the right to cancel this workshop up to 14 calendar days prior to the course start date. Notifications will be emailed immediately upon cancellation and a tuition refund will be issued. FAES will make every effort to retain posted courses. We encourage the purchase of refundable travel reservations in the event that a course is cancelled.

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