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BIOL 039 | Epigenetics

December 7, 2020 to December 11, 2020

Registration occurs on a first-come, first-served basis. The deadline for registration is one week before the first day of the course.  If you are unable to register before the deadline, please email: registrar@faes.org or call 301-496-7977 for space availability. 

NIH Fellows or NIH community members being sponsored by their lab and awaiting payment authorization can tentatively hold a seat using the “Reserve A Seat” option. FAES must receive payment within 7 business days after reserving a seat or 3 business days before the start of the workshop, which ever comes first. If payment is not received in this time frame, your reservation will be canceled.

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Program Description
The sequencing of the human genome was not the endpoint of our goal of understanding human genomics. The chemical modifications to DNA, RNA, and the DNA-bound histone proteins, represent a second level of genetics-related biological control. These phenomena are often termed epigenetics (or epigenomics when evaluated genome-wide), and research has shown that epigenetic mechanisms provide an additional layer of biological control that regulates gene expression, chromatin organization, and DNA integrity.

This course will cover the basic principles of epigenetics, the role of epigenetic mechanisms in different organisms and animal model systems, the relevance of epigenetics to normal development and human disease, and the utilization of drugs and molecules that target epigenetic mechanisms. Furthermore, it provides a background that will facilitate a better understanding of the literature in this rapidly growing field. This course also aims to provide an understanding of epigenetic experimental design, and should, therefore, enable participants to incorporate epigenetic approaches into their research studies. 

Participating instructors are full-time researchers from neighboring institutes and universities who have been publishing in these areas for several years.

Topics
Zoom lectures cover the basic mechanism underlying DNA methylation, histone modification, chromatin organization, noncoding RNA, and gene repression. Moreover, a broad range of topics will be covered in epigenetic research, including cancer, development, environmental health, and immunology. The lectures also provide the participant with practical information concerning current techniques in epigenetic research. For example, the application of CHARM, Illumina bead arrays, restriction enzyme analysis, and bisulfate sequencing is discussed in designing experiments and interpreting data.

In the virtual laboratory workshop, attendees gain experience in techniques including extraction of DNA, bisulfite conversion, methyl specific PCR (QMSP), and QMSP data analysis and interpretation.

The virtual computational lab workshop aims to provide an understanding of the bioinformatic approaches and computational methods used to analyze DNA methylation and chromatin data, as well as an integration of this data with bulk and single-cell gene expression data. Such approaches are relevant to the analysis of data from many cutting-edge technologies and should prove useful for those interested in conducting a variety of epigenetic experiments and research projects.

Training Rate
$1,299.00 - General Rates - All others

Discounted Training Rates
$795.00 - NIH Trainees (Fellows, Postdocs, Postbacs, Grad students workng at any NIH campus)
$995.00 - NIH Community (Working, Appointed, or Assigned to NIH Campus)
$1,099.00 - Academia, US Goverment, US Military

Credit
Although no grades are given for Workshops, each participant will receive Continuing Education Units (CEUs) based on the number of contact hours. Upon completion of this 5-day program, each participant will receive 3.5 CEUs. Upon completion of each workshop, a certificate is issued.

Refund Policy
100% tuition refund for registrations cancelled 14 or more calendar days prior to the start of the workshop.
50% tuition refund for registrations cancelled between 4 to 13 calendar days prior to the start of the workshop.
No refund will be issued for registrations cancelled 3 calendar days or less prior to the start of the workshop.

Notification
All cancellations must be received in writing via email to Ms. Carline Coote at registration@faes.org.
Cancellations received after 4:00 pm (ET) on business days or received on non-business days are time marked for the following business day. 
All refund payments will be processed by the start of the initial workshop.

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