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Wednesday Afternoon Lecture Series (WALS) - A patient-scientist’s road toward primary prevention in genetic prion disease

December 4, 2019

3:00pm - 4:00pm

Building 10, Clinical Center, Lipsett Auditorium

The NIH Director's Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. Lectures occur on most Wednesdays from September through June from 3:00 to 4:00 p.m. in Masur Auditorium, Building 10 on the NIH Bethesda campus.

Each season includes some of the biggest names in biomedical and behavioral research. The goal of the WALS is to keep NIH researchers abreast of the latest and most important research in the United States and beyond. An added treat is the annual J. Edward Rall Cultural Lecture, which features top authors and other cultural icons. All speakers are nominated by the NIH community.

Speaker: Sonia Vallabh, J.D., Ph.D. & Eric Minikel, Ph.D.

In 2010, Sonia Vallabh watched her 52 year old mother die of a rapid, mysterious, undiagnosed neurodegenerative disease. One year later, Sonia learned that her mother's disease had been genetic prion disease, and that she herself had inherited the causal mutation, making it very likely she would suffer the same fate in 20 years' time. There was no prevention, treatment, or cure available. Despite having no prior training in biology, Sonia and her husband Eric Minikel set out to re-train themselves as scientists and devote their lives to searching for a treatment or cure for her disease. They quit their jobs in consulting, started a scientific blog, began taking night classes and attending conferences, found new jobs in research labs, and eventually earned PhDs in biomedical research at Harvard. They are now scientists at the Broad Institute of MIT and Harvard, where their research focuses on biomarker development and preclinical therapeutic testing, all oriented around the goal of primary prevention of prion disease.

 

This lecture will be followed by a reception in the NIH Library. Special thanks to the Foundation for Advanced Education in the Sciences (FAES) for its support of the weekly reception. FAES is proud to co-sponsor with the NIH in hosting the Wednesday Afternoon Lecture Series.

To watch the WALS lecture online, visit http://videocast.nih.gov. Registration is not required; seating is on a first-come, first-served basis. Fire regulations require that every person in Masur Auditorium must have a seat. Standing in the aisles or in the back of the auditorium is not permitted. Sign language interpreters can be provided. Individuals with disabilities who need reasonable accommodation to participate in this event should contact Jacqueline Roberts, Jacqueline.Roberts@nih.gov, 301-594-6747, or the Federal Relay, 800-877-8339.